ocr: Resi dent and Staff Physici an Patient Education Chart Histamine Release Causes Allergy Symptoms Histamine Allergic Reaction Mast cells and basophils body again, it is attracted contain histamine which is to the IgE on the mast cells responsible for the and basophils, and this symptoms related to the causes histamine release. allergic reaction. When the allergen enters the Reprinted with permissionifomResident and: Staff Physician (c)1991-92, 19931 by Romaine Pierson Publishers, Inc.